| ncRNA name | hsa-miR-181a |
| ncRNA Category | miRNA |
| Disease name | choroidal neovascularization (CNV) |
| Species | Homo sapiens |
| Tissues/Cell_line | human retinal endothelial cells (HRECs) , human umbilical vein endothelial cells (HUVECs) |
| Methods | illumina BeadCHIPs, [3H]-thymidine incorporation assay, apoptosis assay, tube formation assay, qRT-PCR |
| Expression pattern | associated |
| Functional description | The inhibition of miR-181a significantly abrogated the effect of LMPs on endothelial viability, but overexpression of miR-181a reduced endothelial cell viability in a dose-dependent manner. miR-181a strongly inhibited in vitro angiogenesis and ex vivo choroidal neovascularization. |
| PubMed ID | 29608244 |
| Year | 2018 |
| Title | microRNA-181a inhibits ocular neovascularization by interfering with vascular endothelial growth factor expression. |
| Drug-related ncRNA | NO |
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